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Terry Etherton Blog on Biotechnology


DHS Firm on Kansas Site for Bio-Defense Research Lab

Sep 1, 2009
By: James M. Lewis
DVM NEWSMAGAZINE

WASHINGTON — Despite a critical report from another agency and a fair amount of political pressure, the Department of Homeland Security (DHS) remains committed to the Manhattan, Kan., site it chose for building a new national bio-defense research laboratory and says it won’t re-open the site-selection process.

As part of the 2010 government appropriations bill, Congress asked the Government Accountability Office (GAO) to conduct a separate study on DHS’s recommendation to move the Level-3 laboratory at Plum Island, N.Y., to Kansas. The study was to evaluate whether it would be safe to conduct research into foot-and-mouth disease (FMD) at a mainland site for the first time, rather than on the offshore island where it’s been handled for decades in an aging facility. Read the rest of this entry »

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H3N2 Brings New Influenza Threat

A ProMED-mail post (August 2, 2009)

Hong Kong’s health authorities announced Wednesday [27 Jul 2009] that a new variant of the H3N2 seasonal influenza virus has been found in the city. The Brisbane strain has been the prevalent circulator of H3N2 in the past year, and the new variant is its direct descendent, said Thomas Tsang, controller of Hong Kong’s Center for Health Protection (CHP). “However, it has some genetic changes distinguishing it from the old Brisbane strain,” he said. He said it is normal for viruses to go through changes, adding that overseas health authorities, including those in Canada, Britain and Australia, had also found the new variant. Read the rest of this entry »

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Infectious Diseases Study Site Questioned

On June 9, 2009, I posted a blog “The Slippery Slope Involved in the Proposed Move of the U.S. Foot and Mouth Disease Lab – What a “Mess!” that questioned the basis for the Department of Homeland Security (DHS) support for the movement of FMD virus and research from the current location at Plum Island Animal Disease Research Center (PIADC) to the newly announced National Bio and Agro-Defense Facility (NBAF) site managed by Kansas State University.  This morning’s Washington Post had a very interesting article that discusses concerns about this issue.  Enjoy reading the story.

By Carol D. Leonnig
Washington Post Staff Writer
Monday, July 27, 2009

The Department of Homeland Security relied on a rushed, flawed study to justify its decision to locate a $700 million research facility for highly infectious pathogens in a tornado-prone section of Kansas, according to a government report. Read the rest of this entry »

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Health Inspectors Caught Swine Flu Investigating Alberta Pig Farm Outbreak

A ProMED-mail post (July 23, 2009)

Two Canadian Food Inspection Agency [CFIA] inspectors appear to have contracted swine flu while investigating an outbreak of the new virus in pigs on an Alberta farm in late April [2009], the agency confirmed on 21 July 2009.

The cases appear to be the first report of people catching the new H1N1 virus from pigs. Read the rest of this entry »

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Risk Factors for Severe Swine Flu a Wide Umbrella Under which Many Stand

A ProMED-mail post (June 19, 2009)

Whether speaking of a 58-year-old man or a 38-year-old woman, or a little boy of 9, officials announcing swine flu deaths are almost always quick to note “underlying health  conditions” may have contributed to the fatal outcome. Asthma, heart disease, diabetes, maybe even obesity are among the conditions used to help explain why swine flu infection is hospitalizing and killing younger people, people who would be expected to make a full recovery from seasonal flu. Read the rest of this entry »

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The Slippery Slope Involved in the Proposed Move of the U.S. Foot and Mouth Disease Lab – What a “Mess”!

Background: Common to all fields of science and engaged scientists is their willingness to participate in the free exchange of ideas. This blog often posts such ideas in the form of existing citable scientific contributions and news items. In recent conversations among like-minded individuals regarding contemporary topics in livestock production agriculture and biotechnology, the issue of U.S. animal disease research was raised. No factor in livestock production can impact production efficiency and profitability more than a disease issue. And, in the case of a highly contagious foreign animal disease (FAD) where the U.S. would change from disease-free status to one of a FAD positive diagnosis, livestock production could be decimated in quick order. Read the rest of this entry »

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INFLUENZA A (H1N1) – SWINE IMMUNITY

A ProMED-mail post (May 28, 2009)

The following is [1] a statement of the research program of the United States Department of Agriculture (USDA) Agricultural Research Service (ARS), and [2] the outcome of a study of the cross-reactivity of serum samples from US pigs against the new swine origin 2009 H1N1 influenza virus (S/O H1N1). The results of this analysis indicate that pre-existing immunity induced by swine influenza viruses circulating in the US may not protect pigs against the new S/O H1N1 influenza virus presently circulating in people.

Read the rest of this entry »

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Devilish Dilemmas Surround Pandemic Flu Vaccine

Martin Enserink and Jocelyn Kaiser
Published in SCIENCE:  VOLUME 324:703-705,2009

If and when a pandemic of H1N1 swine flu hits, vaccines might be the world’s best hope for softening the blow. But major uncertainties cloud the prospects for vaccines against the new  strain. No pandemic vaccine yet exists, and it is unclear how much vaccine would have to be available, and by what time, to have any impact. Should manufacturers halt the production of seasonal influenza vaccine to focus on a pandemic version, and if so, when? And is there any way to ensure that people around the world have an equal chance to get the new vaccine? Read the rest of this entry »

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Assessing the Severity of an Influenza Pandemic

From the World Health Organization

Assessing the Severity of an Influenza Pandemic

The major determinant of the severity of an influenza pandemic, as measured by the number of cases of severe illness and deaths it causes, is the inherent virulence of the virus. However, many other factors influence the overall severity of a pandemic’s impact. Read the rest of this entry »

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Pork Production Practices Help Contain H1N1 Influenza

Bob Mikesell, Ph.D.
Senior Instructor
Department of Dairy and Animal Science

Introduction

In light of the H1N1 (formerly known as swine flu) virus outbreak, consumers should have an understanding of the influenza virus from a pork producer perspective, and the steps that US swine producers routinely utilize to keep pigs healthy. Read the rest of this entry »

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